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Studies of osteoblasts have revealed that GPER activation not only promotes the proliferation and differentiation of osteoblasts, thus affecting bone mineralization via the AMPK/ACC signaling pathway, but also inhibits mitochondrial autophagy in osteoblasts through the activation of the AKT pathway, reducing apoptosis [146]

Acetyl-L-carnitine (ALCAR), the acetyl ester of L-Carnitine, is endogenously synthesized in human or obtained from dietary sources with a higher bioavailability compared to L-carnitine

Therefore, this chapter makes a literature review of the most important general aspects of endogenous antioxidant systems, which will provide another point of view from which to approach the study and treatment of many chronic degenerative diseases, such as diabetes, hypertension, and Parkinson

Enzymes as biocatalysts in the modification of natural lipids

Tirzepatide achieved 22.5% in 72 weeks